PRODUCTION OF INFECTIOUS HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 DOES NOT REQUIRE DEPLETION OF APOBEC3G FROM VIRUS-PRODUCING CELLS

Production of infectious human immunodeficiency virus type 1 does not require depletion of APOBEC3G from virus-producing cells

Abstract Background The human immunodeficiency virus Vif protein overcomes the inhibitory activity of the APOBEC3G cytidine deaminase by prohibiting its packaging into virions.Inhibition of APOBEC3G encapsidation is paralleled by a reduction of its intracellular level presumably caused Novelty by the Vif-induced proteasome-dependent degradation of

read more

Constitution and Identity of Romanians

Strongly rooted in the existential matrix of each people, identity has defining factors that are consecrated, in a political-legal form within their constitutions.The present study reveals the forms and modalities by which the Romanian constitutional acts included not only the political-legal principles of modern Europe, but also the social and cul

read more